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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Glur2 RNA editing ： ウィキペディア英語版 Glur2 RNA editing In genetics, the Gria2 gene is located on chromosome 4q32-q33. The gene product is the ionotropic AMPA glutamate receptor 2 ( also known as Glur2 or GlurB). The protein belongs to a family of ligand-activated glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA). Glutamate receptors function as the main excitatory neurotransmitter at many synapses in the central nervous system. L-glutamate, an excitatory neurotransmitter, binds to the Gria2 resulting in a conformational change. This leads to the opening of the channel converting the chemical signal to an electrical impulse. AMPA receptors (AMPAR) are composed of four subunits, designated as GluR1 (GRIA1), GluR2 (GRIA2), GluR3 (GRIA3), and GluR4(GRIA4) which combine to form tetramers. They are usually heterotrimeric but can be homodimeric.〔http://www.genecards.org/cgi-bin/carddisp.pl?gene=GRIA2&search=glur2〕 Each AMPAR has four sites to which an agonist (such as L-glutamate) can bind, one for each subunit.() ==RNA editing== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Glur2 RNA editing」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.